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TITLEWheat microbiome bacteria can reduce virulence of a plant pathogenic fungus by altering histone acetylation | Nature Communications^^^Close banner^^^Close banner318155
DESCRIPTIONInteractions between bacteria and fungi have great environmental, medical, and agricultural importance, but the molecular mechanisms are largely unknown. Here, we study the interactions between the bacterium Pseudomonas piscium, from the wheat head microbiome, and the plant pathogenic fungus Fusariu11301114
KEYWORDS0
H1Wheat microbiome bacteria can reduce virulence of a plant pathogenic fungus by altering histone acetylation112107
H2 - H6<h2>Abstract</h2>
<h2>Introduction</h2>
<h2>Results</h2>
<h2>Discussion</h2>
<h2>Methods</h2>
<h2>References</h2>
<h2>Acknowledgements</h2>
<h2>Author information</h2>
<h2>Ethics declarations</h2>
<h2>Additional information</h2>
<h2>Electronic supplementary material</h2>
<h2>Rights and permissions</h2>
<h2>About this article</h2>
<h2>Further reading</h2>
<h2>Comments</h2>
<h2>Explore content</h2>
<h2>About the journal</h2>
<h2>Publish with us</h2>
<h2>Search</h2>
<h2>nature.com sitemap</h2>
<h3>Subjects</h3>
<h3>ZJU60 shows strong inhibitory activity against FHB</h3>
<h3>PCN is the major antifungal compound produced by ZJU60</h3>
<h3>PCN mediates the BFI and biofilm formation of ZJU60</h3>
<h3>SAGA complex is critical for PCN sensitivity in Fg</h3>
<h3>PCN specifically targets the HAT activity of FgGcn5 in SAGA</h3>
<h3>SAGA complex regulates growth and virulence of Fg</h3>
<h3>Wheat head microbiome sequencing and analysis</h3>
<h3>Isolation, identification, and antifungal activity of ZJU60</h3>
<h3>Characterization of secondary metabolites in ZJU60</h3>
<h3>Construction of fungal deletion and complementation strains</h3>
<h3>Evaluation of biocontrol efficiency</h3>
<h3>Western blot assay</h3>
<h3>Pathogenicity assays and DON biosynthesis assays</h3>
<h3>Biofilm formation assay</h3>
<h3>Bacterial colonization on fungal mycelium</h3>
<h3>In vitro acetylation assay</h3>
<h3>Determination of PCN–FgGcn5 binding by SPR</h3>
<h3>Data analysis</h3>
<h3>Data availability</h3>
<h3>Affiliations</h3>
<h3>Contributions</h3>
<h3>Corresponding authors</h3>
<h3>Competing interests</h3>
<h3><...>Supplementary Information<...></h3>
<h3><...>Peer Review File<...></h3>
<h3><...>Description of Additional Supplementary Files<...></h3>
<h3><...>Supplementary Movie 1<...></h3>
<h3><...>Supplementary Movie 2<...></h3>
<h3><...>Supplementary Movie 3<...></h3>
<h3><...>Supplementary Data 1<...></h3>
<h3><...>Supplementary Data 2<...></h3>
<h3><...>Supplementary Data 3<...></h3>
<h3><...>Supp		71255min - 6
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Слова отсутствующие в русском и английском словарях

ГдеКол-воСписок слов
TITLE3microbiome histone acetylation
DESCRIPTION11Pseudomonas piscium microbiome Fusarium graminearum histone acetyltransferase acetylation mycotoxin et al
KEYWORDS
H13microbiome histone acetylation
H2 - H626Acknowledgements antifungal biofilm Biofilm Fg microbiome complementation biocontrol Pathogenicity mycelium vitro acetylation transcriptomic proteomic intracellular myriocin Fusarium oxysporum sp niveum Microbiota spp Rhizosphere syntenic Triticum aestivum
Анкоры гиперссылок16PubMed transcriptomic proteomic intracellular myriocin Fusarium oxysporum sp niveum microbiome Microbiota spp Rhizosphere syntenic Triticum aestivum
Текст страницы517Pseudomonas piscium microbiome Fusarium graminearum histone Histone acetyltransferase acetylation Acetylation mycotoxin protists pathogenesis antibiosis physiochemical chemotaxis agroecosystems biocontrol Biocontrol BCAs lipopeptide phenazine Phenazine antifungal Lysobacter enzymogenes ceramide synthase Aspergillus oxysporum fusaric fluorescens chlororaphis phytopathogenic Fg mycotoxins Mycotoxins deoxynivalenol Deoxynivalenol zearalenone culturable biofilms Biofilms hyphae epigenetic rhizosphere rRNA OTUs spp Paenibacillus Sphingomonas commensal vitro planta phenamacril foliar Alternaria alternata Botrytis cinerea verticillioides Magnaporthe grisea Penicillium italicum Sclerotinia sclerotiorum s.d biotypersmart Biotypersmart subsp replicons prophage MITEs phylogenetic nucleotides desorption PacBio bp aroE dnaA guaA gyrB mutL ppsA pyrC recA rpoB genomic Bioinformatics siderophores bacteriocin pyoverdine achromobactin operons phzA-H operon biosynthetic supernatant mycelia Mycelia µg chorismic chromatographic-mass spectrometry Warkingsman mycelium biofilm Biofilm planktonic mycelium-associated peptone PsI polysaccharides ΔphzA-H immunoblotting anti-Psl biofilm-like biotic abiotic pellicle pellicles microtiter Exopolysaccharides exopolysaccharide polysaccharide mannose-rich aeruginosa anti-PsI Saccharomyces cerevisiae μg phenazines Phenazines superoxide dismutase menadione intracellular phosphatases kinases FgPCN PCN-sensitive ΔFgPCN mycelial complementation Complementation ΔFgPCN-C transcriptional subunit FgPcn orthologs ortholog lysine histones recombinant Recombinant immunoblotted ImageJ sensorgrams nM subunits polymerase coli agarose Ni-NTA acetylated plasmon ligand acetyltransferases N-acetyltransferase gramineaum fludioxonil triadimefon transduction myosin sterol hyphal conidia conidiation pathogenicity Pathogenicity anthesis toxisome Toxisome trichothecene toxisomes immunoblot anti-GFP carbendizm carbendazim Carbendazim toxisomal µm anti-GAPDH supernatants nd glumes spikelets qRT-PCR mitogen-activated abolishment hydroxyphenazines pyocyanin phenazine-producing vacuolar ATPase topoisomerase Redox pseudocolor biosynthesized monocytogenes deacetylation deacetylase oomycetes Phytophthora sojae effector Streptomyces rapamycinicus nidulans efficacies enterica niger albicans Arbuscular mycorrhizal farnesol N-acetyl-D-glucosamine homoserine lactones WspR-controlled eDNA MDa Bioinformatic homologs pre-initiation deubiquitinating monoubiquitinated acetylating eukaryotes e.g ribosome biogenesis dimorphic Ustilago maydis sporulation fujikuroi Yannong Anhui Norcross Nanodrop electrophoresis Equimolar hypervariable Axygen Biosciences Illumina MiSeq NaCl Biotyper antiSMASH centrifugation eluted CHCl MeOH Bruker Avance plasmid TaKaRa plasmids auxotroph recombinants kanamycin hygromycin hyg ORFs geneticin Tri-GFP Jimai mid-anthesis conidial Huai Jiangsu Zhejiang Yangmai ImageQuant spikelet confocal SampliQ Agilent μl resuspended nm duplications vortexed gauze